PTPRT, a member of the protein tyrosine phosphatase (PTP) family, has been reported to be a tumour suppressor gene in BC and other cancers.39, 40, 41, 42, 43, 44, 45NCKAP5, potentially functioning in microtubule bundle formation and microtubule depolymerization, is less studied, and polymorphisms in this gene are reported to be associated with the clinical outcome of patients with gastric cancer in a recent study.46 This evidence concerns the gene PTPRT and breast cancer.