We pooled all 20 genes (Stx6, Ramp1, Traf3ip1, Nckap5, Pfkfb2, Trmt1l, Rprd1b, Rer1, Sepsecs, Rhobtb1, Tsen15, Abcc3, Arid5b, Tnr, Dock2, Tti1, Fam81a, Oxr1, Plxna2 and Tbc1d31) together as the mouse tumour susceptibility gene signature (mTSGS). The gene discussed is RHOBTB1; the disease is neoplasm.