We got 38 target genes, in these genes, we found AMOTL1, PIK3R3, TGFBR1, SMO, COL4A6, MGP, SOX4, IGF2, Slit1 and CKS2 genes may contribute to invasion, metastasis and prognosis of central neurocytoma (Fig. 5). The gene discussed is SMO; the disease is central neurocytoma.