GZMB and neoplasm: We also tested T cell secretion of IFN-λ and granzyme B during co-culture with other HER2-positive tumor cells, including A549, A1847, SKBR3, and MDA-MB-231 cells, and consistently observed a dose-dependent induction of IFN-λ and granzyme B by the bsAb (Figure 3G–N).