These receptors have been shown to be crucial in preventing early tumor formation by recognizing stress-induced ligands that are expressed on different types of cancer cells [125,126,127], such as MHC class I-related polypeptide sequence A (MICA) [127,128,129], natural killer cell cytotoxicity receptor 3 ligand 1 (NCR3LG1), and BCL2-associated athanogene 6 (BAG6) [130,131]. The gene discussed is MICA; the disease is neoplasm.