In a study published in 2022 among PLHIV attending an HIV Clinic in Trinidad [14], the HIV-1/HTLV-1-coinfected patients had higher HIV-1 viral loads and more opportunistic infections signifying a worse prognosis, though there were no statistically significant differences in CD4+ counts as compared to the HIV-1 singly infected patients [14]. This evidence concerns the gene CD4 and Opportunistic infection.