TMPRSS2 and infection: The addition of elacridar to Vero E6+TMPRSS2 cells was not toxic (Figure S13a) and did not show an effect on the infection when using SARS-CoV-2 or MERS-CoV virus (Figure S13b,c), but remdesivir and nirmatrelvir showed a significant shift in activity in the presence versus the absence of the P-GP inhibitor (Figure S13d,e).