In an experimental mouse model of AIDS-related CMV retinitis (experimental murine AIDS (MAIDS)-related mouse CMV (MCMV) retinitis), SOCS1 and SOCS3 were found to be involved in signal transduction during viral infection and were related to the severity of experimental MAIDS-related MCMV retinitis [24] (see Section 6. This evidence concerns the gene SOCS3 and retinitis.