Stool DNA-FIT testing (mt-sDNA test) incorporates in FIT the detection of multiple cancer DNA biomarkers from cells shed into stools from the lining of the colon and rectum, such as mutant KRAS, APC, and aberrant methylation of BMP3 (bone morphogenetic protein 3), and NDRG4 (N-myc Downstream-regulated Gene 4). This evidence concerns the gene BMP3 and cancer.