Therefore, a convenient lifestyle accompanied by healthy nutrition, a reduction in energy-dense food consumption, physical activity and activities that reduce oxidative stress are the most common therapeutic strategies to reduce cardiometabolic risk factors closely linked to obesity, such as hypertension, dyslipidemia, insulin resistance, diabetes, elevated levels of fibrinogen and C-reactive protein (CRP), including low-grade chronic inflammation (Figure 1) [1,11]. Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.