The nitrobenzoxadiazole derivative 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX, 46a) (Figure 11B) is a known inhibitor of the human glutathione S-transferases (GSTs) P1-1 and M2-2 (GSTP1-1 and GSTM2-2, respectively) and was previously identified as a potent cytotoxic agent against murine and human cancer cells and against the protozoan parasite Giardia duodenalis [115,116,117]. This evidence concerns the gene HPGDS and cancer.