Other targets for antibodies can be, for instance, the transmembrane protein CXCR4 present on many cancer cells, the epidermal growth factor receptor (EGFR), folate receptors (FR), prostate specific membrane antigen (PSMA) or CD40 antigen, as well as the estrogen receptor (ER), p-glycoproteins and integrins [100,101,102,103,104,105]. The gene discussed is ESR1; the disease is cancer.