This analysis highlighted significant differences in expression levels of several disease-associated genes between the control and HNSCC groups, including TP53, MET, NOTCH1, PTEN, PIK3CA, EGFR, CDKN2A, BRCA1, BRCA2, BRAF, and PALB2 (Figure 6A). This evidence concerns the gene BRCA2 and head and neck squamous cell carcinoma.