CD274 and neoplasm: However, [99mTc]Tc-HYNIC-WL12-tricine/ISONIC displayed significantly lower MC38-B7H1 tumor uptake at 2 h p.i. than that of [99mTc]Tc-HYNIC-WL12-tricine/TPPTS (6.63 ± 0.80%ID/g vs. 18.22 ± 4.57%ID/g).