STX1A and hemolytic-uremic syndrome: Notably, one of the strains associated with HUS belonged to the O104:H21 serotype and ST672 lineage and carried stx1a, stx2d, and ehxA, similar to previously described STEC O104:H21 isolates responsible for an outbreak of haemorrhagic colitis in the United States of America [52] or associated with HUS in Germany [53].