These anti-inflammatory cytokines activate the response to infection through MHC II with the proteins from the parasite for the processing of the antigen and the induction of the production of IgM antibodies that appear on the seventh-day post-infection, as well as in the IgG presenting two weeks after infection [21], thus triggering the production of IL-2 for the development of CD8+ cells. Here, CD40LG is linked to infection.