The intracellular survival signaling pathways activated by Chlamydia infection encompass the polo-like kinase 1/3-phosphoinositide-dependent protein kinase 1/Myc proto-oncogene (PLK1/PDPK1/MYC) signaling pathway, the Raf/MEK/ERK mitogen-activated protein kinase (MAPK) pathway, and the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway [63,64,86,87]. Here, PDPK1 is linked to chlamydia infectious disease.