TP53 and cervical carcinoma: They found that the IC50 values of jujube extract at 24, 48, and 72 h were 1.2, 0.5, and 0.2 mg/mL, respectively, and jujube extract upregulated the expression of P53, P21, and P27 and downregulated the expression of cyclin D1 in cervical cancer cells, thereby limiting the proliferation of cervical cancer cells and reducing the toxicity of cancer cells [87].