In a mouse model of hepatitis B virus-induced HCC, it was noted that SCFA administration reduced the number of dysplastic nodules and HCC in HBx transgenic mice, downregulating some genes critically involved in tumor progression, such as several growth factors, PI3K, Wnt, Vascular Endothelial Growth Factor (VEGF) and Ras [134]. The gene discussed is VEGFA; the disease is neoplasm.