It was shown that there was a statistically significant increase in the chance of developing IBD in heterozygotes for the rs11568820 (Cdx2) polymorphism (OR: 2.3, 95% CI [0.88, 6.18], p = 0.04), in heterozygotes for the rs1544410 (BsmI) polymorphism (OR: 2.07, 95% CI [0.89, 4.82], p = 0.048), and in heterozygotes for the rs731236 (TaqI) polymorphism (OR: 2.18, 95% CI [0.92, 5.2], p = 0.05). Here, CDX2 is linked to inflammatory bowel disease.