However, a greater reduction in serum IFN-γ levels after one month on the low-glutamate diet was marginally associated with a higher likelihood of depression improvement: OR (95% CI) = 1.11 (0.00, 1.42), (p = 0.06) after controlling for age, sex, race, BMI change, and FFQ change. This evidence concerns the gene IFNG and depressive symptom measurement.