GPT and hyperandrogenism: Moreover, a recent meta-analysis of 36 studies that evaluated the prevalence and risk factors of MASLD in patients with PCOS found a pooled MASLD prevalence of 43%, while BMI, waist circumference, alanine aminotransferase (ALT) and HOMA-IR values, levels of free androgen index, hyperandrogenism, and triglycerides were positively correlated with a significantly elevated risk of MASLD among PCOS patients.