Stroke patients more frequently presented with NYHA class III and IV heart failure (p = 0.028), ICA stenosis (p < 0.001), ICA occlusion (p < 0.001), prior carotid artery endarterectomy (p < 0.001), diabetes treated with oral medications (p < 0.001) or insulin (p < 0.001), arterial hypertension (p = 0.032), atrial fibrillation (p < 0.001), and extracardiac arteriopathy (p < 0.001). The gene discussed is INS; the disease is stroke disorder.