However, increased Th1 signal (IFN-γ, CXCL9, CXCL10) and more pronounced Th17/Th22 activation (IL-17A, CCL20, Elafin, and IL-22) were significantly greater in patients with intrinsic AD, even suggesting immunological features of overlap with psoriasis [22]. This evidence concerns the gene CXCL9 and Alzheimer disease.