NOTCH1 and enterocolitis: Besides, Feng et al. explored the underlying mechanism of enteric neural precursor cells (ENPCs) and the ZEB2/Notch-1/Jagged-2 pathway in Hirschsprung’s-associated enterocolitis development by Western blot and RT-qPCR, while bioinformatics analysis and co-immunoprecipitation were utilized to investigate the ZEB2 and Notch-1 interaction [42].