ERBB2 and neoplasm: The currently used blood tests and scanning procedures are expected to be enhanced through their combination with novel nanoparticle-based methods, such as the use of iron oxide nanoparticles (IONPs) for imaging of cancer metastasis in the brain [33], self-illuminating nanoprobes as markers for tumor-infiltrating neutrophils [34], ATP-responsive superparamagnetic iron oxide nanoparticles (SPIOs) [35], and peptide-functionalized magnetic nanoparticles to detect human epidermal growth factor receptor 2 (HER2) on circulating tumor cells [36].