SLC5A2 and infection: Despite the use of SGLT-2 inhibitors, other EDKA-precipitating factors include infection, exertion or physical stress, decreased caloric intake or prolonged fasting, anorexia, persistent vomiting, dehydration, gastroparesis, insulin pump failure, insulin dose reduction/omission, acute pancreatitis, (bariatric) surgery, alcohol use disorder, ketogenic diet, glycogen storage disease, chronic liver disease, newly diagnosed diabetes mellitus, and pregnancy [14,16,19,20].