Tumor cells trigger the coagulation cascade via the tissue factor (TF) and the induction of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-a), interleukin 1 (IL-1), interleukin 6 (IL-6), interleukin 8 (IL-8), and transforming growth factor beta (TGF-b) [13]. This evidence concerns the gene IL6 and neoplasm.