Tumor cells trigger the coagulation cascade via the tissue factor (TF) and the induction of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-a), interleukin 1 (IL-1), interleukin 6 (IL-6), interleukin 8 (IL-8), and transforming growth factor beta (TGF-b) [13]. The gene discussed is TNF; the disease is neoplasm.