The European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), and the European Association for the study of Obesity (EASO) Practice Guidelines recommend implementing the Mediterranean diet for MASLD treatment, as it improves metabolism by reducing insulin resistance and lowering LDL levels and steatosis [29]. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.