Five SNP datasets were strongly associated with periodontitis: ebi-a-GCST90019404 (medium-chain specific acyl-CoA dehydrogenase (MCAD); mitochondrial measurement) [17], prot-a-1907(malonyl-CoA decarboxylase (MLYCD), mitochondrial measurement), prot-a-1220 (glutaredoxin-2 (Grx2); mitochondrial measurement), prot-a-2526 (oligoribonuclease, (ORN); mitochondrial measurement) and prot-a-2190 (pyruvate carboxylase (PC); mitochondrial measurement) [18]. The gene discussed is PC; the disease is periodontitis.