Due to the change in the ROS and RNS production during BMDMs infection with Mtb and RvΔ0687, we further hypothesized this could impact the secretion of cytokines or chemokines and analyzed the levels of IL-1β, TNF-α, MIP-1α and IP-10 cytokines in the supernatants of BMDMs infected with Mtb strains. This evidence concerns the gene TNF and infection.