PTEN and non-small cell lung carcinoma: For H460 and A549 cell lines, the combination of ceralasertib with RT significantly enhanced radiosensitivity in PTEN-depleted NSCLC cells in comparison to NT cells (RER = 2.17 (p ˂ 0.01); RER = 4.05 (p ˂ 0.01), respectively).