IL6 and melanoma: Moreover, ADSCs co-cultured with melanoma cells from different lines (G-361, SK-Mel-5, MeWo, and A2058) increased the migration capacity of malignant cells, which was correlated with the overexpression of genes such as CXCL12, PTGS2, IL-6, IL-8, and, most notably, HGF, and increased the expression of CCL2, IL-6, IL-8, VEGF, MMP-2, and the EMM-PRIN proteins [66].