PC 34:1, PE 36:2, SM d18:1/16:0, HexCer d18:1/24:0, and HexCer d18:1/24:1 were suggested as biomarkers for non-metastatic cancer when compared to controls. On the other hand, PE 34:2, PE 36:2, PE(P-16:0/20:4), and Cer d18:1/24:1 best characterized the metastatic patients. The findings were supported by a cell lines study. The gene discussed is CBLN1; the disease is metastatic malignant neoplasm.