The lipidome analysis revealed 131 significantly upregulated and 115 downregulated lipid metabolites.Eight ceramides were significantly decreased in cancer: Cer (d18:1/20:0), Cer (m18:1/20:0), Cer (m18:1/22:0), Cer (m18:1/22:1), Cer (m18:1/24:1), Cer (d18:1/18:0), Cer (d18:1/20:1) and CerP (d18:1/12:0).Among 20 the most dysregulated lipids, ceramides were the only which were downregulated. Other upregulated lipids included 13 FFAs, 2 PCs, a CE, and an LPC. Here, CBLN1 is linked to cancer.