In the analysis, 10 lipids were found to be upregulated and 31 were downregulated in CRC.10 lipids were selected as the best characterizing CRC form controls; however, only CerP (d15:0_22:0+O) showed good accuracy above AUC > 0.9. Four lipids had significant survival prognostic values: TAG (11:0_18:0_18:0) (HR: 0.34), TAG (18:0_18:0_18:1) (HR: 0.34), PC (22:1_12:3) (HR: 2.22), LPC (17:0) (HR: 3.16). The gene discussed is ABCA1; the disease is colorectal carcinoma.