FABP4 and cardiovascular disorder: As of this writing, the mechanisms underlying these differences between ioFABP4 and ioFABP5 remain to be elucidated, although both FABP4 and FABP5 are expressed in endothelial cells, as well as in adipocytes and macrophages [2], and are secreted into bodily fluids, and both factors are thus involved in the pathophysiological conditions related to several metabolic and cardiovascular diseases [1,68].