TRIM21 and autoimmune disease: Using serum specimens from 184 patients with autoimmune diseases and 50 controls, Qin et al. evaluated the analytical and clinical performance of line immunoassays, multiplex bead-based flow fluorescent immunoassays, and magnetic bar code immunoassays for the detection of antinuclear antibodies, including those targeting Ro60 and Ro52; they found that the three assays showed good agreement [119].