Following early reports on the association between blood groups and the occurrence of infection [9,10], and an initial examination of a handful of candidate genes, based on their association with other viral interactions, such as ACE2, CLEC4M, MBL, ACE, CD209, FCER2, OAS-1, TLR4, and TNF-α [11,12,13], in the years since, several hundred genes have been implicated to play a role in the complex host genetic contribution to COVID-19. Here, MBL2 is linked to COVID-19.