Six TLRs recognize the presence of SARS-CoV-2 (TLR2, TLR3, TLR4, TLR7, TLR8, and TLR9), of which TLR2, TLR4, and TLR9 favor the pathogenicity of the virus, while TLR3, TLR7, and TLR8 favor control of the infection and resolution of the disease [100]. The gene discussed is TLR9; the disease is infection.