A recent membrane proteomics and tissue microarray study evaluated the role of brain acid soluble protein 1 (BASP1), a protein implicated in the biochemical pathway of Wilms tumor protein (WT1), in predicting the outcome of patients with PC, showing its association with prolonged survival and a better response to adjuvant chemotherapy treatment than in patients in whom the same marker is negative [49]. The gene discussed is BASP1; the disease is pachyonychia congenita.