ACh is a key protective molecule in heart disease, which acts through the parasympathetic branches of the autonomic nervous system and sympathetic nervous system [58], as well as in isoallol-induced CH [59,60], acute myocardial infarction [61], Ang II-induced cardiac dysfunction [62], and other conditions that can exert cardiovascular protection. The gene discussed is AGT; the disease is cyclic hematopoiesis.