For example, isocitrate dehydrogenase 1-antisense 1 (IDH1-AS1) [131], which negatively regulates the Warburg effect in multiple cancer types, including colon and cervical cancers, by promoting the homodimerisation of isocitrate dehydrogenase 1, the protein produced by the IDH1 locus [131]. The gene discussed is IDH1; the disease is cancer.