In agreement with this possibility, GATA1 translation is reduced in erythroid precursor cells of DBA patients with mutations in different r-protein genes (e.g., [219,220,221]), and loss-of-function mutations in GATA1 result in a DBA-like phenotype (e.g., [222,223] and references therein). This evidence concerns the gene TCN1 and Diamond-Blackfan anemia.