In clear cell renal cell carcinoma (ccRCC), a circRNA from the transportin 3 (TNPO3) gene, circ-TNPO3, directly binds to the IGF2BP2 protein, destabilizing SERPINH1 mRNA and inhibiting ccRCC cell proliferation [156]. The gene discussed is TNPO3; the disease is clear cell renal carcinoma.