The CRC prediction model based on 13 PRGs (AIM2, CASP1, CASP5, CASP6, CASP8, CASP9, ELANE, GPX4, GSDMD, NLRP7, NOD2, PJVK, and PRKACA) revealed a higher proportion of immune infiltration and better survival outcomes in the low-risk group [156]. The gene discussed is CASP1; the disease is colorectal carcinoma.