The glycoprotein CD147 is dimethylated to CD147-K234me2 by lysine methyltransferase 5A (KMT5A); overexpression of CD147-K234me2 and KMT5A enhances glycolysis and lactate export in non-small cell lung cancer (NSCLC) cells [76]. The gene discussed is KMT5A; the disease is non-small cell lung carcinoma.