Jones et al. performed deep-sequencing analysis studies and identified several recurrent mutations in already-known medulloblastoma-related genes such as CTNNB1, PTCH1, MLL2, and SMARCA4, as well as a new set of genes not linked to this tumor before; this set included DDX3X, CTDNEP1, KDM6A, and TBR1 [9]. The gene discussed is DDX3X; the disease is medulloblastoma.