Moosavi et al. reported that in studies of Cao2 colorectal adenocarcinoma cells, extracellular vehicles EVs derived from gut microbiota such as F. prausnitzii increase the permeability of the intestinal barrier, among others, through the PPARα, PPARγ and PPAR β/δ genes [180]. The gene discussed is PPARG; the disease is colorectal adenocarcinoma.