ACE2 and hyperlipidemia: Statins, commonly used drugs to treat hyperlipidemia by blocking cholesterol synthesis [54], showed no effects on ACE2 maturation in our screening (Figure 6A,B), while other chemical inhibitors, such as methyl-β-cyclodextrin, which removes cholesterol from plasma [55] showed slightly improved ACE2 maturation (Figure 5L); meaning that ACE2 levels are maintained normal and are not subjected to reduced availability.