To mention some examples, in relation to psoriasis, INSP supernatants from donors with lichen showed higher levels of DAG1 [FC = 3.6; p = 0.005], cartilage acidic protein 1 (CRAC1) [FC = 3.0; p = 0.005], Calumenin (CALU) [FC = 6.6; p = 0.006], erythrocyte band 7 integral membrane protein (STOM) [FC = 11; p = 0.008], RAS-related protein Rap-1b (RAP1B) [FC = 5.5; p = 0.008], the complement C9 (CO9) [FC = 1.4; p = 0.02], or coagulation factors X (FA10) [FC = 2.1; p = 0.03] and XIII (F13A) [FC = 1.5; p = 0.05]. The gene discussed is GREM1; the disease is psoriasis.