TNFSF13B and autoimmune disease: Current BAFF-directed therapies that are undergoing clinical trials for use in autoimmune disease include belimumab, tabalumab (LY2127399), blisibimod (A-623), ianalumab (VAY736), atacicept, povetacicept (ALPN-303), rozibafusp alfa (AMG-570), and BAFF CAR-T.