The immunological data initially analyzed included anti-nuclear autoantibodies (AAN), IgG anti-dsDNA autoantibodies, IgG autoantibodies against extractable nuclear antigens (ENA), including autoantibodies directed against RNP, SSA/Ro (60 kDa), SSB/La, Sm, centromere, Scl-70 and Jo-1. Here, CALR is linked to Balkan nephropathy.